Tetrabutylammonium Fluoride → HCID 86718427, compound

Participants

Reaction Steps

The compound obtained in step (2) (6.22 g) was dissolved in THF (200 ml), TBAF (a 1.0 M THF solution, 11.6 ml) was added under stirring, and stirring was conducted for 4 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified by flash chromatography (ethyl acetate/hexane=50%→100%) using an amino column (trade name: Hi-Flash Column 3L Amino, manufactured by Yamazen Corporation) to give the title compound (1.61 g).

Provenance & Evidence