Water → 2,4,7-Trimethylocta-2,6-dien-1-ol

Participants

Reaction Steps

To a suspension of LiAlH4 (4.8 g, 126 mmol) in THF (100 ml) was added dropwise a solution of 2,4,7-trimethylocta-2,6-dienal (20 g, 114 mmol) in THF (60 ml) at 5° C. over 1 h. The mixture was stirred at room temperature for 1 h. 5 ml of water, 5 ml of 15% aq. NaOH and 15 ml of water were carefully added subsequently. The mixture was stirred for 1 h. Precipitates were filtered and the filtrate was concentrated in vacuo. The residue was Kugelrohr-distilled to give 2,4,7-trimethylocta-2,6-dien-1-ol (98%). bp: 82-83° C./1 mbar.

Provenance & Evidence