Cesium carbonate → HCID 67984390, compound

Participants

Reaction Steps

In a stream of argon, 0.50 g (0.94 mmol) of 2-(3,3″-dichloro-(1,1′:3′,1″-terphenyl-5′-yl)-4,6-diphenylpyrimidine, 0.67 g (4.16 mmol) of benzofurylboronic acid, 1.35 g (4.16 mmol) of cesium carbonate, 8 mg (0.038 mmol) of palladium acetate and 36 mg (0.075 mmol) of 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl were suspended in 20 mL of 1,4-dioxane, and the obtained suspension was heated under reflux for 14 hours. The reaction mixture was cooled to room temperature, and was then distilled under a reduced pressure to remove all volatile materials. Methanol was added to the concentrate, and the thus-deposited solid was collected by filtration. The thus-obtained crude product was purified by silica gel chromatography using a hexane/chloroform (1/1) mixed solvent as an eluent to give 0.16 g of the target 2-[3,3″-di(2-benzofuryl)-1,1′:3′,1″-terphenyl-5′-yl]-4,6-diphenylpyrimidine as a white solid (yield: 25%).

Provenance & Evidence