Diethyl Ether → HCID 57500378, compound

Participants

Reaction Steps

17 ml (0.22 mol) of trifluoroacetic acid are added to the suspension of 7.95 g (10.9 mmol) of benzyl 5-[(1-{[3-(2-tert-butoxy-2-oxoethoxy)benzoyl]amino}-2-methylindolizin-3-yl)carbonyl]-2-[(trifluoroacetyl)amino]benzoate in 55 ml of dichloromethane at ambient temperature. The mixture becomes rapidly homogenized. The solution is stirred for 3 hours and concentrated to dryness. The solid obtained is taken up with ethyl ether, filtered and dried. 7.25 g (99%) of an orange powder are obtained.

Provenance & Evidence