HCID 52951820, compound → HCID 66945606, compound

Participants

Reaction Steps

This compound was prepared, starting from compound 24 (0.35 g, 0.83 mmol), according to the procedure developed for compound 36. Reaction time at room temperature: 28 h; the purification was performed using column chromatography (Al2O3, CH2Cl2/EtOH, 98/2, v/v) to give compound 54 (0.27 g, 0.76 mmol) as a beige solid. Yield 92%; Rf (Al2O3, CH2Cl2/EtOH, 98/2, v/v) 0.28; 1H NMR (200 MHz, CDCl3) δ 1.18 (t, 3H, J=7.1 Hz), 1.57 (se, 1H), 2.76 (q, 2H, J=7.1 Hz), 2.97 (t, 2H, J=6.1 Hz), 3.68 (q, 2H, J=6.0 Hz), 7.83 (d, 1H, J=8.8 Hz), 8.08 (dd, 1H, J=1.9, 8.8 Hz), 8.34 (m, 1H), 8.60 (d, 1H, J=1.9 Hz), 9.65 (s, 1H).

Provenance & Evidence