N-[2-[N-ethyl-N-[2-(2-fluoropyridin-3-yloxy)ethyl]amino]ethyl]-6-iodoquinoline-2-carboxamide → N-[2-[N-ethyl-N-[2-(2-fluoropyridin-3-yloxy)ethyl]amino]ethyl]-6-iodoquinoline-2-carboxamide dihydrochloride salt

Participants

Reaction Steps

This compound was prepared, starting from compound 67 (0.20 g, 0.39 mmol), according to the procedure developed for compound 11. Reaction time at room temperature: 12 h to give compound 68 (184 mg, 0.32 mmol) as a very hygroscopic beige solid. Yield 81%; mp 99-101° C. (dec.); IR (KBr) ν 1255, 1385, 1465, 1559, 1645, 2500-3500 cm−1.

Provenance & Evidence