HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Hydroxyethyl)pyridine → 2-(Pyridin-2-yl)ethyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Hydroxyethyl)pyridine | HCID 7675 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(Pyridin-2-yl)ethyl methanesulfonate | HCID 22637034 | — |
Reaction Steps
A solution of 2-pyridin-2-yl-ethanol (Aldrich, 0.11 mL, 0.99 mmol), triethylamine (0.42 mL, 3.0 mmol), and methanesulfonyl chloride (0.12 mL, 1.5 mmol) in 5 mL THF were processed as described in Example 1C to give the crude title compound which was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560481B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-86d982c59fa645749bfc02de3d136a90 |
| Source note | uspto-grants-2009_07 |