HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-(Tetrahydro-2H-pyran-4-yl)ethyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-(Oxan-4-yl)ethan-1-ol | HCID 17750944 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(Tetrahydro-2H-pyran-4-yl)ethyl methanesulfonate | HCID 22273083 | — |
Reaction Steps
The product of Example 8A (2.9 mmol), triethylamine (1.2 mL, 8.7 mmol) and methanesulfonyl chloride (0.34 mL, 4.4 mmol) in 10 mL tetrahydrofuran (THF) were reacted and the product isolated as in Example 1C to give the title compound that was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560481B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-cab984eb0dbd4e83a9687a4e09548263 |
| Source note | uspto-grants-2009_07 |