HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 2-Pyridin-4-ylethyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 4-Pyridineethanol | HCID 72921 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Pyridin-4-ylethyl methanesulfonate | HCID 44627228 | — |
Reaction Steps
The 4-(2-hydroxyethyl)pyridine (Lancaster, 0.153 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560481B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-27c1f926c44d42dfaaecf57c873ae410 |
| Source note | uspto-grants-2009_07 |