HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4,4,4-Trifluorobutyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 4,4,4-Trifluorobutan-1-ol | HCID 136307 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4,4,4-Trifluorobutyl methanesulfonate | HCID 22725681 | — |
Reaction Steps
The 4,4,4-trifluoro-1-butanol (Lancaster, 0.16 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560481B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-79893ca73396434482432e8dae0be832 |
| Source note | uspto-grants-2009_07 |