HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → Nelotanserin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | 2,4-Difluorophenyl isocyanate | HCID 593258 | — |
| Reactant | 3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyaniline | HCID 11572741 | — |
| Product | Nelotanserin | HCID 11683556 | — |
Reaction Steps
reacting 3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenylamine with 2,4-difluorophenyl-isocyanate in the presence of a urea-forming solvent to form 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126946B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-925b9ca4779f49f2afde3b5280fbce58 |
| Source note | uspto-grants-2015_09 |