1-Fluorocyclopropyl Methyl ketone → HCID 68326403, compound

HRID 2274008Notes

Reaction equation

HRID 2274008 reaction equation
[F:1][C:2]1([C:5](=O)[CH3:6])[CH2:4][CH2:3]1.ClC1(C2C=[C:15]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[N:14]([CH3:22])[N:13]=2)CC1>>[F:1][C:2]1([C:5]2[CH:6]=[C:15]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[N:14]([CH3:22])[N:13]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 111371091-Fluorocyclopropyl Methyl ketoneHCID 68326448HCID 68326448, compound

Product 1

HCID 68326403HCID 68326403, compound

Procedure

Ethyl 3-(1-fluorocyclopropyl)-1-methyl-1H-pyrazole-5-carboxylate is prepared from 1-(1-fluorocyclopropyl)ethanone analogously to the process described in the synthesis of ethyl 3-(1-chlorocyclopropyl)-1-methyl-1H-pyrazole-5-carboxylate.

Sources & evidence

ORD record
ord-9b1568b5d2ed4cc6923b7544d607ed2a
Source dataset
uspto-grants-2015_09
Patent number
US09126945B2

Reaction notes

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