HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274141Generated: October 30, 2026
Formamide → 7-Bromo-3,4-dihydroquinazolin-4-one
https://huagongshe.com/reaction/2274141
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 2-Amino-4-bromobenzoic acid | HCID 88691 | — |
| Product | 7-Bromo-3,4-dihydroquinazolin-4-one | HCID 135555612 | — |
Reaction Steps
340.0 g (1.56 mol) of 2-amino-4-bromobenzoic acid were suspended in 970 ml of formamide and subsequently stirred at 170° C. for 12 h. Conventional work-up gave 326.0 g of 7-bromo-3H-quinazolin-4-one; HPLC/MS (M+H)+=226 as solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09126952B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-447c6eb755b149b3bc34f9518b46303b |
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| Source note | uspto-grants-2015_09 |
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