関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Urea | HCID 1176 | — |
| 反応物 | 2-Amino-5-bromo-4-methoxybenzaldehyde | HCID 59325258 | — |
| 生成物 | HCID 178486882 | HCID 178486882 | 89.8% |
反応手順
A mixture of 2-amino-5-bromo-4-methoxybenzaldehyde (3 g, 13.1 mmol) and urea (12 g, 196.5 mmol) was stirred at 180° C. for 2 h. LCMS showed the reaction was completed. The reaction mixture was cooled to RT and washed with water (3×100 mL). The precipitate was collected and dried to give the title compound (3 g, crude) as a yellow solid. MS (ES+) C8H7BrN2O2 requires: 254, 256. Found: 255, 257 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09126951B2 |
|---|
| 出典データセット | uspto-grants-2015_09 |
|---|
| ORD ID | ord-6464423adbb74348be1f22b0926b4ed8 |
|---|
| 出典メモ | uspto-grants-2015_09 |
|---|
