HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → 4-Acetamido-3-nitrobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Acetamido-3-nitrobenzoic acid | HCID 73758 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Acetamido-3-nitrobenzoyl chloride | HCID 13354056 | — |
Reaction Steps
4-Acetamido-3-nitrobenzoic acid 1 (Alfa Aesar, 5.6 g, 25 mmol), oxalyl chloride (4.76 g, 38 mmol), chloroform (50 ml), DMF (few drops) were stirred at 40° C. for 3 hours. The solvent was removed in vacuo to give a yellow solid that was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126961B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-8b3aea8008e749688ffeb3ce241dc4ca |
| Source note | uspto-grants-2015_09 |