2,2-Diethoxyethylamine → HCID 10682842, compound

HRID 2274659Notes

Reaction equation

HRID 2274659 reaction equation
[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH2:6])[CH3:2].Br[CH2:11][CH2:12][C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14]>>[CH2:1]([O:3][CH:4]([O:7][CH2:8][CH3:9])[CH2:5][NH:6][CH2:11][CH2:12][C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH3:2]

Participants

3

Reactant 2

HCID 695242,2-DiethoxyethylamineHCID 256128tert-Butyl 3-bromopropionate

Product 1

HCID 10682842HCID 10682842, compoundYield 25%

Procedure

According to the procedure described in the synthesis method of Compound IX-1, 2,2-diethoxyethanamine (5.82 ml, (40 mmol) was reacted with tert-butyl 3-bromopropionate (3.34 ml, 20 mmol) and the obtained residue was purified by Büch silica gel column chromatography (eluent: chloroform only) to obtain the title compound (1.33 g, 25%).

Workup

  1. customthe obtained residue was purified by Büch silica gel column chromatography (eluent

Sources & evidence

ORD record
ord-39a1940b447b498c9276cb043ae2cbd6
Source dataset
uspto-grants-2015_09
Patent number
US09126981B2

Reaction notes

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