HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picolyl chloride hydrochloride → HCID 178420438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picolyl chloride hydrochloride | HCID 23392 | — |
| Reactant | HCID 178527937 | HCID 178527937 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178420438 | HCID 178420438 | — |
Reaction Steps
1 (0.33 g, 1.5 mmol), TEA (0.418 mL, 3.0 mmol) and (pyridin-2-yl)methylchloride hydrochloride (0.246 g, 1.5 mmol) were dissolved in 10 mL of EtOH and kept under reflux overnight. The solvent was removed and the remaining oil was purified by flash-chromatography on silica gel, applying a CHCl3/MeOH gradient.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126987B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-5e86e6e774804f25bbc05970df1c11c3 |
| Source note | uspto-grants-2015_09 |