HCID 66700347, compound → HCID 71183362, compound

HRID 2274744Notes

Reaction equation

HRID 2274744 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[CH2:7][N:8]1[C:14](=[O:15])[C:13]2[CH:16]=[C:17]([C:20]3[CH:25]=[CH:24][C:23](OC(F)(F)F)=[CH:22][CH:21]=3)[CH:18]=[CH:19][C:12]=2[O:11][CH2:10][CH2:9]1.[F:31][C:32](OB(C1C=CC=CC=1)O)([F:34])[F:33]>>[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[CH2:7][N:8]1[C:14](=[O:15])[C:13]2[CH:16]=[C:17]([C:20]3[CH:21]=[CH:22][C:23]([C:32]([F:34])([F:33])[F:31])=[CH:24][CH:25]=3)[CH:18]=[CH:19][C:12]=2[O:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 66700347HCID 66700347, compoundHCID 71183216Eleclazine

Product 1

HCID 71183362HCID 71183362, compound

Procedure

Compound 2 is prepared in a manner similar to that of Compound 1 except that 4 trifluoromethyl phenyl boronic acid is used in place of 4-trifluoromethoxy phenyl boronic acid.

Sources & evidence

ORD record
ord-149a874a9e7f47f880dfafd07973beb1
Source dataset
uspto-grants-2015_09
Patent number
US09126989B2

Reaction notes

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