Pivaloyl chloride → HCID 118060107, compound

Participants

Role	Name	HCID	Charge
Reactant	Pivaloyl chloride	HCID 62493	—
Reactant	6-fluoro-1-(phenylsulfonyl)-3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-indole hydrochloride	HCID 118060305	—
Product	HCID 118060107	HCID 118060107	104.6%

Reaction Steps

Following the general method as outlined in Example 89, starting from 6-fluoro-1-(phenylsulfonyl)-3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-indole hydrochloride (Intermediate 17; 200 mg; 0.47 mmol) and pivaloyl chloride (0.12 mL; 0.98 mmol), 250 mg (>100%) of the title compound was obtained as a yellow solid, which was used directly without further purification.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09126984B2
Source dataset	uspto-grants-2015_09
ORD ID	ord-95fb0f5399494f4eae1685427f617e90
Source note	uspto-grants-2015_09