Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274845Generated: October 31, 2026

HCID 118060468, compound → HCID 118059904, compound

https://huagongshe.com/reaction/2274845

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 118060468HCID 118060468—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 118059904HCID 11805990474.5%

Reaction Steps

A mixture of 3-(1-(3,6-dichloropyridazin-4-yl)-1H-pyrazol-4-yl)-6-fluoro-1-(phenylsulfonyl)-1H-indole (Step 1; 80 mg; 0.16 mmol) and Pd/C (30 mg; 10%) in MeOH (15 mL) was stirred for 1 hour under a hydrogen balloon. The reaction mixture was filtered and concentrated to afford 50 mg (64%) of the title compound as a yellow solid, which was used directly without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09126984B2
Source datasetuspto-grants-2015_09
ORD IDord-69126f5acdb94bc9a595e8bb417b6623
Source noteuspto-grants-2015_09