HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Pteridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Chloropteridine | HCID 640537 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Pteridine | HCID 1043 | — |
Reaction Steps
Treatment of chloro-pteridine V′ with nuclephile R7LY, in the presence of a base, such as sodium hydride, potassium carbonate, triethylamine, and diisopropylethylamine, and optionally using a catalyst such as Pd(0), affords Pteridine compound VI′. Suitable solvent for this reaction includes chloroform, methylene chloride, toluene, and tetrahydrofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09126996B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-3166ba63d6fd45aea0cc1985aa6a7402 |
| Source note | uspto-grants-2015_09 |