HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2274996Generated: October 31, 2026
Iodoethane → 1-Ethyl-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde
https://huagongshe.com/reaction/2274996
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1H-Pyrrolo(2,3-b)pyridine-2-carbaldehyde | HCID 21873680 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-Ethyl-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde | HCID 86340174 | — |
Reaction Steps
In a separate reaction: To a suspension of 1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde (600 mg, 4.11 mmol) and Cs2CO3 (2675 mg, 8.21 mmol) in N,N-Dimethylformamide (DMF) (20 mL) stirred under nitrogen at 20° C. was added iodoethane (0.498 mL, 6.16 mmol) dropwise during 0.5 min. The reaction mixture was stirred at r.t. for 1 h, TLC showed complete conversion.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09127003B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-cd52baf1bd9949548ad3a9399eb9de8b |
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| Source note | uspto-grants-2015_09 |
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