HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22591566, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-methoxy-6-(N-benzylindole-5-sulfonyl)-2H-pyridazine | HCID 22591548 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22591566 | HCID 22591566 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A mixture of 3-methoxy-6-(N-benzylindole-5-sulfonyl)-2H-pyridazine (0.64 mmol, 245 mg), conc. HCl (0.5 mL), and dioxane (3 mL) was heated at 100° C. for 2 hours. The reaction mixture was cooled and evaporated to dryness. Water (10 mL) was added to the residue and the resulting solid, 6-(N-benzylindole-5-sulfonyl)-2H-pyridazin-3-one, was collected (55%, 102 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849629B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-bc7eb3559db7427dadb479243e8efc7a |
| Source note | uspto-grants-2005_02 |