tert-butyl N-(2-hydroxyethyl)carbamate → [2-(3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)-ethyl]-carbamic acid tert-butyl ester

HRID 2275070노트

반응식

HRID 2275070 반응식
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:22])([CH3:21])[C:6]=2[CH:23]=1.[C:24]([O:28][C:29](=[O:34])[NH:30][CH2:31][CH2:32]O)([CH3:27])([CH3:26])[CH3:25]>>[C:24]([O:28][C:29](=[O:34])[NH:30][CH2:31][CH2:32][O:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:21])([CH3:22])[C:6]=2[CH:23]=1)([CH3:27])([CH3:26])[CH3:25]

참가 물질

3

반응물 2

HCID 2733206tert-butyl N-(2-hydroxyethyl)carbamateHCID 668338618-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

생성물 1

HCID 68092739[2-(3-Cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yloxy)-ethyl]-carbamic acid tert-butyl ester

실험 절차

Under the same conditions as the method for synthesizing Compound A7-1, the title compound was prepared from Compound A6 and (2-hydroxy-ethyl)-carbamic acid tert-butyl ester.

후처리

  1. customUnder the same conditions as the method for synthesizing Compound A7-1

출처 및 근거

ORD 기록
ord-519335be91404d528e79794e473bb6eb
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09126931B2

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