8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile → HCID 178431646, compound

HRID 2275083Notes

Reaction equation

HRID 2275083 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:22])([CH3:21])[C:6]=2[CH:23]=1.[C:24]([SiH2:28][O:29][C:30]([CH3:41])([CH3:40])[C@@H:31]1[O:35][C:34]([CH3:37])([CH3:36])[O:33][C@@H:32]1[CH2:38]O)([CH3:27])([CH3:26])[CH3:25]>>[C:24]([SiH2:28][O:29][C:30]([CH3:40])([CH3:41])[C@H:31]1[O:35][C:34]([CH3:37])([CH3:36])[O:33][C@@H:32]1[CH2:38][O:1][C:2]1[CH:3]=[CH:4][C:5]2[C:17](=[O:18])[C:16]3[C:15]4[C:10](=[CH:11][C:12]([C:19]#[N:20])=[CH:13][CH:14]=4)[NH:9][C:8]=3[C:7]([CH3:21])([CH3:22])[C:6]=2[CH:23]=1)([CH3:27])([CH3:25])[CH3:26]

Participants

3

Reactant 2

HCID 668338618-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 131733422HCID 131733422, compound

Product 1

HCID 178431646HCID 178431646, compound

Procedure

Under the same conditions as the method for synthesizing Compound A7-1, the title compound was prepared from Compound A6 and [(4R,5R)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-methanol.

Workup

  1. customUnder the same conditions as the method for synthesizing Compound A7-1

Sources & evidence

ORD record
ord-cfa6185561ef4f3d8025ad31a19402ef
Source dataset
uspto-grants-2015_09
Patent number
US09126931B2

Reaction notes

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