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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2275116Generated: October 25, 2026

1-(Methylsulfonyl)piperazine → 6,6-dimethyl-8-(4-(methylsulfonyl)piperazin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/reaction/2275116

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Methylsulfonyl)piperazineHCID 709161—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product6,6-dimethyl-8-(4-(methylsulfonyl)piperazin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 54586753—

Reaction Steps

Under the same conditions as the method for synthesizing Compound B2-1, the title compound was prepared from Compound B1 and 1-methanesulfonylpiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09126931B2
Source datasetuspto-grants-2015_09
ORD IDord-d318776719354156872034243179a6b1
Source noteuspto-grants-2015_09