6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one → HCID 66834007, compound
Reaction equation
[Br:1][C:2]1[CH:14]=[C:13]2[C:5]([C:6]3[C:7](=O)[C:8]4[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:9]=4[C:10]([CH3:16])([CH3:15])[C:11]=3[NH:12]2)=[CH:4][CH:3]=1.[Br:24]C1C=C2C(=CC=1OC)C(C)(C)C(=O)CC2>>[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:13]2[C:14]=1[C:6]1[CH2:7][C:8]3[CH:20]=[C:19]([Br:24])[C:18]([O:21][CH3:22])=[CH:17][C:9]=3[C:10]([CH3:15])([CH3:16])[C:11]=1[NH:12]2Participants
3
Procedure
Under the same conditions as the method for synthesizing Compound A4, the title compound was prepared (as a mixture) from Compound E1.
Sources & evidence
- ORD record
- ord-9be575eda68240a1b6f4f971ef1d99df
- Source dataset
- uspto-grants-2015_09
- Patent number
- US09126931B2
Reaction notes
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