HCID 66835059, compound → Trifluoromethanesulfonic acid 2-cyano-10,10-dimethyl-5-oxo-10,11-dihydro-5H-1,11-diaza-benzo[b]fluoren-8-yl ester

HRID 2275264Notes

Reaction equation

HRID 2275264 reaction equation
[C:1]([C:3]1C=[C:14]2[C:6]([C:7]3[C:8](=[O:30])[C:9]4[CH:21]=[CH:20][C:19]([O:22][S:23]([C:26]([F:29])([F:28])[F:27])(=[O:25])=[O:24])=[CH:18][C:10]=4[C:11]([CH3:17])([CH3:16])[C:12]=3[NH:13]2)=[CH:5][CH:4]=1)#[N:2].OC1C=CC2C(=O)C3C4C=CC(C#N)=NC=4[NH:39]C=3C(C)(C)C=2C=1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[C:7]3[C:8](=[O:30])[C:9]4[CH:21]=[CH:20][C:19]([O:22][S:23]([C:26]([F:29])([F:27])[F:28])(=[O:24])=[O:25])=[CH:18][C:10]=4[C:11]([CH3:16])([CH3:17])[C:12]=3[NH:13][C:14]=2[N:39]=1)#[N:2]

Participants

3

Reactant 2

HCID 66835059HCID 66835059, compoundHCID 86663817Trifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl ester

Product 1

HCID 86663828Trifluoromethanesulfonic acid 2-cyano-10,10-dimethyl-5-oxo-10,11-dihydro-5H-1,11-diaza-benzo[b]fluoren-8-yl ester

Procedure

According to the method used for synthesizing Compound B1, 8-hydroxy-10,10-dimethyl-5-oxo-10,11-dihydro-5H-1,11-diaza-benzo[b]fluorene-2-carbonitrile was subjected to trifluoromethanesulfone esterification to obtain the title compound.

Sources & evidence

ORD record
ord-64356bc6e73e46b48fd2e47d56e800ff
Source dataset
uspto-grants-2015_09
Patent number
US09126931B2

Reaction notes

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