HCID 66835174, compound → HCID 86663830, compound

HRID 2275270Notes

Reaction equation

HRID 2275270 reaction equation
C(C1C=C2C(C3C(=O)C4C=CC([O:22][S:23]([C:26]([F:29])([F:28])[F:27])(=O)=[O:24])=CC=4C(C)(C)C=3N2)=CC=1)#N.[CH2:31]([C:33]1[C:54]([OH:55])=[CH:53][C:36]2[C:37]([CH3:52])([CH3:51])[C:38]3[NH:39][C:40]4[N:41]=[C:42]([C:49]#[N:50])[CH:43]=[CH:44][C:45]=4[C:46]=3[C:47](=[O:48])[C:35]=2[CH:34]=1)[CH3:32]>>[C:49]([C:42]1[CH:43]=[CH:44][C:45]2[C:46]3[C:47](=[O:48])[C:35]4[CH:34]=[C:33]([CH2:31][CH3:32])[C:54]([O:55][S:23]([C:26]([F:29])([F:28])[F:27])(=[O:24])=[O:22])=[CH:53][C:36]=4[C:37]([CH3:52])([CH3:51])[C:38]=3[NH:39][C:40]=2[N:41]=1)#[N:50]

Participants

3

Reactant 2

HCID 66835174HCID 66835174, compoundHCID 86663817Trifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl ester

Product 1

HCID 86663830HCID 86663830, compound

Procedure

According to the method used for synthesizing Compound B1, 7-ethyl-8-hydroxy-10,10-dimethyl-5-oxo-10,11-dihydro-5H-1,11-diaza-benzo[b]fluorene-2-carbonitrile was subjected to trifluoromethanesulfone esterification to obtain the title compound.

Sources & evidence

ORD record
ord-60b8e56eb4fd4d7d9653619ec8b59ccc
Source dataset
uspto-grants-2015_09
Patent number
US09126931B2

Reaction notes

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