反应详情

17.5 g (40.18 mmol) of 10-biphenyl-4-yl-12,12-dimethyl-10,12-dihydro-10-azaindeno[2,1-b]fluorene are suspended in 450 ml of acetonitrile, and 7.15 g (40.18 mmol) of N-bromosuccinimide are added in portions at −20° C. at such a rate that the reaction temperature does not rise above −20° C. The mixture is stirred for a further 18 h, during which the temperature is allowed to come to RT. The reaction mixture is subsequently evaporated in a rotary evaporator, dissolved in dichloromethane and washed with water. The residue is dried, evaporated and subsequently recrystallised from toluene to a purity of 99.3%, giving 10.9 g (53%) of the product as a white solid.

1. customdoes not rise above −20° C
2. customto come to RT
3. customThe reaction mixture is subsequently evaporated in a rotary evaporator
4. dissolutiondissolved in dichloromethane
5. washwashed with water
6. customThe residue is dried
7. customevaporated
8. customsubsequently recrystallised from toluene to a purity of 99.3%