Trifluoromethanesulfonic acid → HCID 89651412, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3,3a,4,4a,5,6,7,8b-octahydro-1H-indeno[1,2-b]pyrrol-2-one (600 mg, 3.38 mmol) in chloroform-d-3 (4 mL) under argon was added triflic acid (0.152 mL) and the solution was stirred 4 h at 40° C. The solution was cooled down and passed through celite, washed with dichloromethane and evaporated. Purification by flash chromatography (ethyl acetate) gave 3,3a,4,5,6,7,8,8b-octahydro-1H-indeno[1,2-b]pyrrol-2-one (322 mg, 53%) as an orange oil. LCMS (Method B): 0.76 min; ES+ 178 (M+H+).

Provenance & Evidence