HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylsulphamoyl chloride → N-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-ylmethyl)-N',N'-dimethylsulfamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylsulphamoyl chloride | HCID 83372 | — |
| Reactant | 1-(4-Aminomethyl-thiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methylphenyl)-urea | HCID 59732816 | — |
| Product | N-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-ylmethyl)-N',N'-dimethylsulfamide | HCID 59732875 | 89.3% |
Reaction Steps
N-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-4-ylmethyl}-N′,N′-dimethylsulfamide (104 mg, 89%) was prepared from 1-(4-aminomethyl-thiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea (90 mg, 0.25 mmol) and dimethylsulfamoyl chloride (0.06 mL, 0.5 mmol) following the general procedure T.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE045670E1 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-28deb95ab19f4a11952993d84964bb08 |
| Source note | uspto-grants-2015_09 |