huagongshe.com
HRID2276218

反应详情

EQUATION

反应方程式

HRID 2276218 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1
HCID59732797

1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea

C17H18BrN3O2S

结构：CN(C)CCn1nnnc1S
HCID178483731

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(NC(=O)Nc2ncc(Sc3nnnn3CCN(C)C)s2)c(C(=O)C2CCCC2)c1
HCID59732713

未命名化合物

收率 25%

PROCEDURE

实验过程

1-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-3-{5-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanyl]-thiazol-2-yl}-urea (125 mg, 25%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and 1-(2-dimethylamino-ethyl)-1H-tetrazole-5-thiol (346 mg, 2 mmol) following the general procedure Y