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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2276233Generated: October 30, 2026

Methylamine → HCID 59732693, compound

https://huagongshe.com/reaction/2276233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 59732813HCID 59732813—
ProductHCID 59732693HCID 5973269365%

Reaction Steps

2-(2-{3-[5-Fluoro-2-(2-methoxy-benzoyl)-phenyl]-ureido}-thiazol-4-yl)-N-methyl-acetamide (144 mg, 65%) was prepared from (2-{3-[5-fluoro-2-(2-methoxy-benzoyl)-phenyl]-ureido}-thiazol-4-yl)-acetic acid (215 mg, 0.5 mmol) and 1N solution of methyl amine in THF (0.5 mL, 0.5 mmol) following the general procedure K.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE045670E1
Source datasetuspto-grants-2015_09
ORD IDord-6d60334ed7e948f9807aed0f8cec6a76
Source noteuspto-grants-2015_09