HCID 86725183, compound → HCID 86725186, compound

HRID 2276358Notes

Reaction equation

HRID 2276358 reaction equation
[F:1][C:2]1[CH:14]=[CH:13][C:5]2[CH2:6][C@H:7](OC)[B:8]([OH:10])[O:9][C:4]=2[C:3]=1[C:15]([OH:17])=[O:16].[NH2:18][C:19]1[S:20][C:21]([SH:24])=[N:22][N:23]=1>>[NH2:18][C:19]1[S:20][C:21]([S:24][C@H:7]2[CH2:6][C:5]3[CH:13]=[CH:14][C:2]([F:1])=[C:3]([C:15]([OH:17])=[O:16])[C:4]=3[O:9][B:8]2[OH:10])=[N:22][N:23]=1

Participants

3

Reactant 2

HCID 86725183HCID 86725183, compoundHCID 178509208HCID 178509208, compound

Product 1

HCID 86725186HCID 86725186, compound

Procedure

Compound 23 was prepared from Compound 19G (example 19) following methods described in steps 5 and 6 of Example 1 utilizing 2-amino-5-mercapto-1,3,4-thiadiazole.

Sources & evidence

ORD record
ord-9f34cc229e3d4aa3b82f6009d90fe18c
Source dataset
uspto-grants-2015_09
Patent number
US09132140B2

Reaction notes

Loading…