HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)benzoic acid → N-{2-[3-chloro-5-(trifluoromethyl)-2-Pyridinyl]butyl}-2-(trifluoromethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)benzoic acid | HCID 9899 | — |
| Reactant | 2-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1-butanamine | HCID 16037439 | — |
| Reactant | 4-(4,6-Dimethoxy[1.3.5]triazin-2-yl)-4-methylmorpholinium chloride hydrate | HCID 23149411 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-{2-[3-chloro-5-(trifluoromethyl)-2-Pyridinyl]butyl}-2-(trifluoromethyl)benzamide | HCID 86612328 | — |
Reaction Steps
100 mg of 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1-butanamine (0.0004 mol), 58 μL of 2-(trifluoromethyl)benzoic acid(0.0004 mol), 0.109 g of 4-(4,6-dimethoxy[1.3.5]triazin-2-yl)-4-methylmorpholinium chloride hydrate (0.0004 mol) are stirred in 2 mL of ethanol at room temperature overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560567B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-4df16ea28b544249987f7ce2a0ad5b62 |
| Source note | uspto-grants-2009_07 |