HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → HCID 70981314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 3-fluoro-N-hydroxy-benzimidoyl chloride | HCID 71438709 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 70981314 | HCID 70981314 | 70% |
Reaction Steps
In a similar manner as described in Preparation Example 17, by using methanol (160 mL), 3-fluoro-N-hydroxybenzimidoyl chloride (8.00 g, 46.09 mmol), methylacetoacetate (10.07 g, 92.18 mmol) and sodium methoxide (7.47 g, 138.27 mmol), a white solid required compound (7.60 g, 32.14 mmol, 70%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09132126B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-e35d00a10a5c434a9794cb428a4268c0 |
| Source note | uspto-grants-2015_09 |