Methyl cyanoacetate → HCID 70981114, compound

Participants

Reaction Steps

In a similar manner as described in Preparation Example 17, by using methanol (160 mL), N-hydroxy-3-(trifluoromethoxy)benzimidoylchloride (8.00 g, 33.39 mmol), methylcyanoacetate (4.31 g, 43.41 mmol) and sodium methoxide (3.61 g, 66.78 mmol), a white solid required compound (8.42 g, 27.87 mmol, 83%) was obtained.

Provenance & Evidence