Hydrochloric Acid → HCID 66666541, compound

Participants

Reaction Steps

To rac-Methyl 7-(2,3-dip-tolyl-7,8-dihydropyrido[2,3-b]pyrazin-5(6H)-yl)-3,4-dihydroxyheptanoate (Step 2) (30 mg, 0.061 mmol) in methanol (1 ml) was added 2M NaOH (0.061 ml, 0.123 mmol). The solution was stirred at room temperature for 3 h. 2M HCl (0.061 ml) was added and the solution was evaporated to dryness. The crude product was purified by chromatography on silica eluting with 0-15% DCM/MeOH to afford the title compound;

Provenance & Evidence