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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2276590Generated: October 31, 2026

4,4'-Difluorobenzil → 2,3-Bis(4-fluorophenyl)-7-methyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine

https://huagongshe.com/reaction/2276590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4'-DifluorobenzilHCID 123072—
Reactant5-Methylpyridine-2,3-diamineHCID 10701825—
Product2,3-Bis(4-fluorophenyl)-7-methyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazineHCID 66666514—

Reaction Steps

The title compound was prepared from 5-methylpyridine-2,3-diamine and 1,2-bis(4-fluorophenyl)ethane-1,2-dione analogously to Intermediate E;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09132127B2
Source datasetuspto-grants-2015_09
ORD IDord-27a5f0a0dd6f467c86acbc2d7936af2f
Source noteuspto-grants-2015_09