HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclopenten-1-one → (S)-3-(4-Bromophenyl)cyclopentan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclopenten-1-one | HCID 13588 | — |
| Reactant | 4-Bromophenyl-boric acid | HCID 315513 | — |
| Catalyst | Binap, (A+-)- | HCID 634876 | — |
| Product | (S)-3-(4-Bromophenyl)cyclopentan-1-one | HCID 25002103 | 91.3% |
Reaction Steps
4-Bromophenylboric acid (3.61 g, 18 mmol), cyclopentenone (0.50 mL, 6.0 mmol) and (S)-BINAP (224 mg, 0.36 mmol) were used and treated in a similar manner to (Step 1) of (Example 1) to give the title compound (1.31 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133140B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-2755166f682548b584e3764bb02e3e5b |
| Source note | uspto-grants-2015_09 |