3-(4-Fluorophenyl)-5-nitro-1H-indazole → 3-(4-fluorophenyl)-1H-indazol-5-amine

Participants

Reaction Steps

The product from Step (c) (0.5 g, 1.94 mmol) was dissolved in methanol (50 ml) and treated with 5 wt % Palladium on charcoal (0.15 g). The reaction mixture was pressurized with 50 psi of H2 and stirred for 4 hours. The reaction was filtered and concentrated in vacuo to afford the title compound (0.36 g, 81%); MS (ES+) m/e 229 [M+H]+.

Provenance & Evidence