Methyl morpholine oxide → HCID 54333143, compound

Participants

Reaction Steps

(E)-3-Methyl-2-octenol (XX; 3 g; 21.4 mmol) was dissolved in 45 ml CH2Cl2. To the solution, was added 10 g 4A° molecular sieves (Aldrich), NMO (4.9 g; 41.8 mmol; Aldrich) and TPAP (0.44 g; 1.25 mmol; Aldrich). The suspension was stirred in the dark under argon for 30 min. The product was purified via silica chromatography (eluent: CH2Cl2). XXI was unstable and was used the same day or stored under argon at −78° C.

Provenance & Evidence