HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 227703Generated: November 2, 2026
5-Nitroindazole → 3-Chloro-5-nitro-1H-indazole
https://huagongshe.com/reaction/227703
Participants
| Role | Name | HCID | Charge |
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| Reactant | 5-Nitroindazole | HCID 21501 | — |
| Reactant | Sodium Hypochlorite | HCID 23665760 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Chloro-5-nitro-1H-indazole | HCID 178526493 | — |
Reaction Steps
5-Nitro-1H-indazole (2.0 g, 12.3 mmol) was suspended in 40 ml ethanol and sodium hypochlorite solution (123 ml, 2.0 M, 246 mmol) was added. The mixture was heated to 75° C. and stirred overnight. The solvent was evaporated to dryness to afford the title compound. (2.4 g, 100%), MS (ES+) m/e 198 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07560467B2 |
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| Source dataset | uspto-grants-2009_07 |
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| ORD ID | ord-6468a862fffb4c8b906fda5a82da030c |
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| Source note | uspto-grants-2009_07 |
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