1H-Indole-6-carboxaldehyde → HCID 90406024, compound

HRID 2277082Notes

Reaction equation

HRID 2277082 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]=O)[CH:8]=2)[CH:3]=[CH:2]1.[NH2:12][C:13]1[CH:14]=[C:15]([C@H:19]([OH:23])[CH2:20][C:21]#[N:22])[CH:16]=[CH:17][CH:18]=1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH2:10][NH:12][C:13]3[CH:14]=[C:15]([C@H:19]([OH:23])[CH2:20][C:21]#[N:22])[CH:16]=[CH:17][CH:18]=3)[CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 27734351H-Indole-6-carboxaldehydeHCID 90406445HCID 90406445, compound

Product 1

HCID 90406024HCID 90406024, compound

Procedure

Reaction between 1H-indole-6-carbaldehyde and (R)-3-(3-aminophenyl)-3-hydroxypropanenitrile gives (R)-3-(3-(((1H-indol-6-yl)methyl)amino)phenyl)-3-hydroxypropanenitrile.

Sources & evidence

ORD record
ord-9c792b2c982e42758bf5e788e4399e7c
Source dataset
uspto-grants-2015_09
Patent number
US09133154B2

Reaction notes

Loading…