HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azide → HCID 86709857, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azide | HCID 33558 | — |
| Reactant | P,P-Diphenylphosphinic azide | HCID 199401 | — |
| Reactant | HCID 86709858 | HCID 86709858 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 86709857 | HCID 86709857 | — |
Reaction Steps
reacting 2-(2,6-dioxo-piperidin-3-yl)-6-methoxy-1,3-dioxo-2,3-dihydro-1H-isoindole-4-carboxylic acid with (a) an azide compound, in one embodiment, DPPA; in the presence of (b) a base, in one embodiment, an organic base, in another embodiment, triethylamine; to form 4-amino-2-(2,6-dioxo-piperidin-3-yl)-6-methoxy-isoindole-1,3-dione; and
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133161B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-1c7f3c8bf3bf47febfee68c0de59832e |
| Source note | uspto-grants-2015_09 |