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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277137Generated: October 31, 2026

HCID 86731192, compound → HCID 136341404, compound

https://huagongshe.com/reaction/2277137

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86731192HCID 86731192—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
ProductHCID 136341404HCID 13634140487.9%

Reaction Steps

A mixture of N-((2S)-1-((2-(4-(benzyloxy)-3-fluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide (1.22 g), 10% palladium-carbon (containing water (50%), 1.00 g) and THF (20 mL) was stirred at room temperature for 20 min under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure. The obtained solid was washed with diethyl ether to give the title compound (850 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-3cde705e72d34e7b81cdd1b8f72dcfff
Source noteuspto-grants-2015_09