Isopropyl iodide → HCID 86731195, compound

HRID 2277140Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]3[CH:17]=[C:16]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:25])[CH3:24])[CH3:21])[CH:15]=[CH:14][C:12]=3[N:13]=2)[CH:5]=[CH:6][C:7]=1[OH:8].[CH:26](I)([CH3:28])[CH3:27]>>[F:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]3[CH:17]=[C:16]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:25])[CH3:24])[CH3:21])[CH:15]=[CH:14][C:12]=3[N:13]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH:26]([CH3:28])[CH3:27]

Participants

Reactant 2

HCID 6362Isopropyl iodide

HCID 136341404HCID 136341404, compound

Product 1

HCID 86731195HCID 86731195, compound

Procedure

Using N-((2S)-1-((2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide and isopropyl iodide, and in the same manner as in Example 5, the title compound was obtained.

Sources & evidence

ORD record: ord-83f535c76b744784b495a192816d82b4
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09133129B2

Reaction notes

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