Isobutylene oxide → HCID 86731197, compound

HRID 2277142Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]3[CH:17]=[C:16]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:25])[CH3:24])[CH3:21])[CH:15]=[CH:14][C:12]=3[N:13]=2)[CH:5]=[CH:6][C:7]=1[OH:8].[O:26]1[C:28]([CH3:30])([CH3:29])[CH2:27]1>>[F:1][C:2]1[CH:3]=[C:4]([C:9]2[O:10][C:11]3[CH:17]=[C:16]([O:18][CH2:19][C@@H:20]([NH:22][C:23](=[O:25])[CH3:24])[CH3:21])[CH:15]=[CH:14][C:12]=3[N:13]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH2:27][C:28]([OH:26])([CH3:30])[CH3:29]

Participants

Reactant 2

HCID 11208Isobutylene oxide

HCID 136341404HCID 136341404, compound

Product 1

HCID 86731197HCID 86731197, compound

Procedure

Using N-((2S)-1-((2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide and 1,2-epoxy-2-methylpropane, and in the same manner as in Example 5, the title compound was obtained.

Sources & evidence

ORD record: ord-030b5021d301451f98acb4462099eb2a
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09133129B2

Reaction notes

Loading…