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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277145Generated: October 30, 2026

Trimethylsilyl isocyanate → 1-((2S)-1-((2-(4-(cyclopropylmethoxy)-3-fluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)urea

https://huagongshe.com/reaction/2277145

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilyl isocyanateHCID 70696—
ReactantHCID 86731188HCID 86731188—
Product1-((2S)-1-((2-(4-(cyclopropylmethoxy)-3-fluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)ureaHCID 86731200—

Reaction Steps

Using tert-butyl ((2S)-1-((2-(4-(cyclopropylmethoxy)-3-fluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)carbamate and trimethylsilyl isocyanate, and in the same manner as in Example 10, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-68a62f742ded48cfb642018b2d02f91b
Source noteuspto-grants-2015_09